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Value of Endolymphatic Hydrops and Perilymph Signal Intensity in Suspected Ménière Disease

J M van Steekelenburg1, A van Weijnen2, L M H de Pont3

  • 1From the Departments of Radiology (J.M.v.S., L.M.H.d.P., S.H.) j.vansteekelenburg@hagaziekenhuis.nl.

AJNR. American Journal of Neuroradiology
|February 8, 2020
PubMed
Abstract

Insights

Combining endolymphatic hydrops and perilymphatic enhancement on MRI improves Ménière disease diagnosis. This dual imaging approach enhances diagnostic accuracy for definite Ménière disease in patients with vertigo.

Area of Science:

  • Neurology
  • Radiology
  • Otolaryngology

Background:

  • Ménière disease is characterized by endolymphatic hydrops.
  • Perilymphatic enhancement on MRI may aid in Ménière disease diagnosis.

Purpose of the Study:

  • Evaluate endolymphatic hydrops and perilymphatic enhancement in Ménière disease patients.
  • Assess the diagnostic value of these findings in differentiating Ménière disease from other inner ear pathologies.

Main Methods:

  • 220 patients with suspected Ménière disease underwent 3D-FLAIR MRI post-gadolinium injection.
  • Endolymphatic hydrops and perilymphatic enhancement were assessed visually and quantitatively.
  • Patients were categorized into definite Ménière disease or other inner ear pathology groups.

Main Results:

  • Endolymphatic hydrops was found in 91.9% of definite Ménière disease cases.
  • The combination of hydrops and enhanced perilymphatic enhancement was present in 81.9% of definite Ménière disease ears.
  • This combination increased the positive predictive value to 0.97.

Conclusions:

  • The combined presence of perilymphatic enhancement and endolymphatic hydrops improves the diagnosis of definite Ménière disease.
  • This MRI finding combination offers significant diagnostic value for Ménière disease.

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