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Related Concept Videos

Cis-regulatory Sequences02:02

Cis-regulatory Sequences

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Cis-regulatory sequences are short fragments of non-coding DNA that are present on the same chromosomes as the genes that they regulate. These fragments serve as binding sites for transcriptional regulators, proteins that are responsible for controlling gene transcription and differential gene expression across cell types in eukaryotes. Cis-regulatory sequences can be close to the gene of interest or thousands of bases away in the DNA sequence; however, those sequences that are further away are...
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Cis-regulatory Sequences02:02

Cis-regulatory Sequences

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Overview of Transposition and Recombination02:13

Overview of Transposition and Recombination

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Transposons make up a significant part of genomes of various organisms. Therefore, it is believed that transposition played a major evolutionary role in speciation by changing genome sizes and modifying gene expression patterns. For example, in bacteria, transposition can lead to conferring antibiotic resistance. Movement of transposable elements within the genetic pool of pathogenic bacteria can aid in transfer of antibiotic-resistant genetic elements. In eukaryotes, transposons can carry out...
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Cooperative Binding of Transcription Regulators02:13

Cooperative Binding of Transcription Regulators

7.1K
Transcriptional regulators bind to specific cis-regulatory sequences in the DNA to regulate gene transcription. These cis-regulatory sequences are very short, usually less than ten nucleotide pairs in length. The short length means that there is a high probability of the exact same sequence randomly occurring throughout the genome.  Since regulators can also bind to groups of similar sequences, this further increases the chances of random binding. Transcriptional regulators form...
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Cooperative Binding of Transcription Regulators02:13

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Master Transcription Regulators02:23

Master Transcription Regulators

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Master transcription regulators are regulatory proteins that are predominantly responsible for regulating the expression of multiple genes. Often these genes work in concert to drive a  complex process. Activation of a master transcription regulator can lead to a cascade of transcriptional activation necessary for that outcome. These regulators can directly bind to the regulatory sequences of the various genes involved, or they can indirectly regulate transcription by binding to regulatory...
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Related Experiment Video

Updated: Dec 29, 2025

Lateral Root Inducible System in Arabidopsis and Maize
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Lateral Root Inducible System in Arabidopsis and Maize

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Author Correction: Widespread long-range cis-regulatory elements in the maize genome.

William A Ricci1, Zefu Lu2, Lexiang Ji3

  • 1Department of Plant Biology, University of Georgia, Athens, GA, USA.

Nature Plants
|February 8, 2020
PubMed
Summary

This study has been amended. Please refer to the updated version for the latest findings and analysis.

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Area of Science:

  • This research falls within the scope of scientific publishing and academic communication.

Background:

  • An amendment to the original paper has been issued.
  • This indicates a need for readers to consult the revised version.

Purpose of the Study:

  • To inform readers about a published amendment.
  • To direct readers to the updated version of the paper.

Main Methods:

  • The primary method involves publishing an amendment notice.
  • Access to the amended paper is provided via a link.

Main Results:

  • An amendment to the paper is now available.
  • The updated version can be accessed through a provided link.

Conclusions:

  • Readers should consult the amended paper for accurate information.
  • The amendment ensures the integrity and currency of the published research.