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A BODIPY-based fluorescent sensor for the detection of Pt2+ and Pt drugs
Fung-Kit Tang1, Jiaqian Zhu2, Fred Ka-Wai Kong3
1Department of Chemistry, State Key Laboratory of Environmental and Biological Analysis, Hong Kong Baptist University, Kowloon Tong, Hong Kong SAR, P. R. China. cfleung@hkbu.edu.hk.
Abstract:
A BODIPY-based fluorescent sensor PS with an NO4S2 podand ligand was studied for the selective detection of Pt2+ over 21 cations as well as selected platinum drugs in aqueous medium. The platinum sensor PS shows 28-fold, 22-fold and 14-fold fluorescence turn-on enhancements to Pt2+, cisplatin and nedaplatin, and was thereby employed to detect platinum drugs in A-549 human lung cancer cells.

