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Rho-ROCK Signaling in Normal Physiology and as a Key Player in Shaping the Tumor Microenvironment

Sean Porazinski1,2, Ashleigh Parkin1, Marina Pajic3,4

  • 1Personalised Cancer Therapeutics Lab, The Kinghorn Cancer Centre, Sydney, NSW, Australia.

Advances in Experimental Medicine and Biology
|February 8, 2020
PubMed

Keywords:
Actomyosin cytoskeletonDevelopmentDiseaseExtracellular matrixMetastasisPancreatic cancerROCK inhibitorsRho-ROCK signalingStromaTargeted therapyTumor microenvironment

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