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Value of CHA2DS2-VASc Score for Prediction and Ruling Out of Acute Stent Thrombosis After Primary Percutaneous

Sadık Kadri Açikgöz1, Eser Açikgöz2, Gökhan Çiçek3

  • 1Department of Cardiology, Kahramankazan Hamdi Eriş State Hospital, Ankara, Turkey.

Angiology
|February 8, 2020
PubMed

Insights

The CHA2DS2-VASc score predicts acute stent thrombosis after percutaneous intervention for ST-segment elevated myocardial infarction. A score of 1 or less indicates a low risk, aiding clinical decision-making.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Thrombosis Research

Background:

  • Acute stent thrombosis is a critical complication following stent implantation.
  • The CHA2DS2-VASc score is established for predicting prognosis in cardiovascular conditions.
  • Identifying risk factors for acute stent thrombosis is crucial for patient outcomes.

Purpose of the Study:

  • To assess the predictive value of the CHA2DS2-VASc score for acute stent thrombosis.
  • To evaluate the CHA2DS2-VASc score in patients undergoing primary percutaneous intervention for ST-segment elevated myocardial infarction.

Main Methods:

  • Retrospective analysis of 2732 patients undergoing primary percutaneous intervention.
  • Exclusion of patients with intraprocedural stent thrombosis or complications.
  • Calculation and analysis of CHA2DS2-VASc scores in relation to acute stent thrombosis events.

Main Results:

  • Acute stent thrombosis occurred in 48 (2.1%) patients.
  • The median CHA2DS2-VASc score was significantly higher in patients with acute stent thrombosis.
  • The CHA2DS2-VASc score was an independent predictor of acute stent thrombosis (OR 1.390, P=.003).
  • A CHA2DS2-VASc score ≤1 demonstrated 91% specificity for predicting the absence of acute stent thrombosis.

Conclusions:

  • The CHA2DS2-VASc score is a valuable tool for predicting acute stent thrombosis in STEMI patients undergoing PCI.
  • A low CHA2DS2-VASc score (≤1) can help identify patients at low risk for acute stent thrombosis.
  • Further research is warranted to integrate this finding into clinical practice.

Keywords:
CHA2DS2-VASc scoreST-segment elevation myocardial infarctionacute stent thrombosisprimary percutaneous coronary intervention

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