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Updated: Dec 29, 2025

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas
Published on: September 13, 2019
Non seminomatous mixed germ cell tumor of the testis with predominant component of somatic type malignancy
Mayur Kothiya1, Sonal Bhandare1, Shaila Khubchandani1
1Department of Histopathology, Jaslok Hospital and Research Centre, Mumbai, Maharashtra, India.
Abstract:
Testicular germ cell tumors (GCT) are a diverse group of neoplasms, broadly divided into seminomatous and non seminomatous types, with varying histomorphology. Mixed germ cell tumors express more than one germ cell component. Somatic type malignancy occurring in testicular GCT is rare. Most often these components present as metastasis, particularly following chemotherapy, rather than primarily involving the testis. We describe a rare case of a young adult with no significant past history, who presented with testicular mass which on histology revealed a non-seminomatous mixed germ cell tumor with additional somatic type malignancy component of a rhabdomyosarcoma.
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