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Related Experiment Video

Updated: Dec 29, 2025

Modeling the Functional Network for Spatial Navigation in the Human Brain

Modeling the Functional Network for Spatial Navigation in the Human Brain

Published on: October 13, 2023

Visual Organization of the Default Network.

Martin Szinte^1,2, Tomas Knapen^1,2

¹Department of Cognitive Psychology, Vrije Universiteit Amsterdam, Amsterdam 1081BT, Netherlands.

Cerebral Cortex (New York, N.Y. : 1991)

|February 8, 2020

Summary

This summary is machine-generated.

The default network (DN) deactivates selectively based on visual stimulus position. This suggests the DN encodes spatial vision through deactivation, functioning as high-level visual regions.

Keywords:

Human Connectome Project deactivation default network population receptive field ultra-high-field fMRI

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Area of Science:

Neuroscience
Cognitive Neuroscience
Computational Neuroimaging

Background:

The default network (DN) is a brain network active during rest and deactivated during cognitive tasks.
The precise role of DN deactivation, particularly in visual perception, remains poorly understood.

Purpose of the Study:

To investigate the role of default network deactivation in visual processing.
To determine if spatial information is encoded within the DN through deactivation patterns.

Main Methods:

Utilized computational neuroimaging techniques.
Analyzed a large dataset from the Human Connectome Project (HCP).
Included data from two individual subjects scanned over multiple repeated runs.

Main Results:

Demonstrated that the DN selectively deactivates in response to the spatial position of visual stimuli.
Showed that spatial vision is encoded within the DN via deactivation relative to a baseline state.
Identified specific high-level visual regions within the DN.

Conclusions:

The default network plays a role in processing spatial visual information.
DN deactivation is a mechanism for encoding visual stimuli.
Suggests the DN functions as a set of high-level visual areas, enabling the application of vision-science methodologies to study its cognitive functions.