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Lower sensitivity to peripheral hypermetropic defocus due to higher order ocular aberrations.

Petros Papadogiannis1, Dmitry Romashchenko1, Peter Unsbo1

  • 1Department of Applied Physics, Royal Institute of Technology (KTH), Stockholm, Sweden.

Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)
|February 8, 2020
PubMed
Summary

Higher-order aberrations (HOA) significantly influence peripheral vision asymmetry in defocus, impacting myopia control strategies. Correcting HOA, not chromatic aberrations, reduces this asymmetry by improving sensitivity to hypermetropic defocus.

Keywords:
asymmetrydefocusmyopiaperipheral vision

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Area of Science:

  • Ophthalmology
  • Optometry
  • Vision Science

Background:

  • Myopia control interventions often aim to alter peripheral refraction.
  • Individuals with myopia exhibit asymmetric responses to myopic and hypermetropic defocus.
  • Understanding factors contributing to peripheral defocus asymmetry is crucial for effective myopia management.

Purpose of the Study:

  • To investigate the role of chromatic aberrations (CA) and higher-order monochromatic aberrations (HOA) in peripheral defocus asymmetry.
  • To determine how CA and HOA influence visual acuity responses to defocus in the periphery.

Main Methods:

  • Peripheral visual acuity was measured in subjects with induced myopic and hypermetropic defocus.
  • Measurements were conducted under conditions with and without CA and HOA correction.
  • Adaptive optics were used to correct for HOA.

Main Results:

  • Peripheral defocus asymmetry was pronounced when natural HOA and CA were present.
  • Eliminating CA had minimal effect on the asymmetry.
  • Adaptive optics correction of HOA significantly reduced peripheral defocus asymmetry, primarily by increasing sensitivity to hypermetropic defocus.

Conclusions:

  • Higher-order monochromatic aberrations are the primary drivers of peripheral defocus asymmetry.
  • Chromatic aberrations play a minor role in this asymmetry.
  • Correcting HOA is key to mitigating peripheral defocus asymmetry, potentially impacting myopia control strategies.