Related Experiment Video
Updated: Dec 29, 2025
10:13
Author Spotlight: An Efficient Methodology to Confidently Differentiate and Characterize Fentanyl Analogs
Published on: November 8, 2024
2.7K
The Opioid Epidemic: America's Epidemic
Instructional Course Lectures
|February 8, 2020
Summary
The opioid epidemic necessitates improved pain management strategies for surgeons. Comprehensive approaches using multimodal options can enhance pain control and reduce opioid side effects.
Area of Science:
- Pain Management and Surgery
- Public Health and Opioid Crisis
Background:
- The United States opioid epidemic significantly impacts medical practice.
- Surgeons require enhanced tools and resources for effective pain management.
Purpose of the Study:
- To outline strategies for surgeons to better understand and manage postoperative pain.
- To emphasize the integration of non-opioid and opioid modalities for comprehensive pain control.
Main Methods:
- Review of current pain management tools and resources.
- Discussion of communication strategies and expectation setting.
- Emphasis on preoperative planning for postoperative pain.
Main Results:
- Understanding pain, setting expectations, and diagnosing predisposing factors for addiction are crucial.
- Multimodal treatment plans incorporating physical, mental, and medicinal options improve outcomes.
Conclusions:
- Integrating comprehensive pain management, including non-opioid alternatives, is essential for minimizing opioid side effects.
- Standardizing pain assessment and management protocols can address the challenges posed by the opioid epidemic.
More Related Videos
09:54Combining Laser Capture Microdissection and Microfluidic qPCR to Analyze Transcriptional Profiles of Single Cells: A Systems Biology Approach to Opioid Dependence
Published on: March 8, 2020
5.6K
16:02Demonstration of the Sequence Alignment to Predict Across Species Susceptibility Tool for Rapid Assessment of Protein Conservation
Published on: February 10, 2023
3.1K
Related Concept Videos
01:15Opioid Analgesics: Synthetic and Semisynthetic Opioids
829
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
829
01:20Opioid Analgesics: Morphine and Other Natural Cogeners
766
Opioids are a class of drugs that mimic endogenous opioid peptides and act on opioid receptors, and help in pain relief. These compounds are classified as natural, synthetic, or semi-synthetic. Natural opioids, like morphine, codeine, and thebaine, are derived from the opium poppy plant (Papaver somniferum or Papaver album) and are termed opiates. Synthetic opioids are artificial, while semi-synthetic opioids combine natural and synthetic compounds. Morphine, a prototypical opioid, possesses a...
766
01:25Analgesia and Pain Management
1.4K
Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...
1.4K
01:22Opioid Receptors: Overview
3.7K
Opioid receptors, including the mu (μ, MOR), delta (δ, DOR), and kappa (κ, KOR) types, belong to the rhodopsin family of G protein-coupled receptors. These receptors are located throughout the central and peripheral nervous systems and in non-neuronal tissues such as macrophages and astrocytes. Opioid receptor ligands can be categorized into agonists or antagonists. Highly selective agonists include [d-Ala2, MePhe4, Gly(ol)5]-enkephalin or DAMGO for MOR, [D-Pen2,...
3.7K
01:02Prescription, Nonprescription and Orphan Drugs
1.1K
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
1.1K
01:15Drug Abuse and Addiction: Pharmacological Phenomena
1.0K
Drug dependence, abuse, and addiction are complex phenomena that can precipitate various abnormal states. Physical dependence refers to a state of pharmacological adaptation to a drug. This adaptation often results in tolerance—a reduced response to the drug after repeated administrations. When the drug use is abruptly stopped, withdrawal symptoms occur due to the body's need to readjust from the pharmacologically induced imbalance. However, tolerance and withdrawal symptoms do not...
1.0K