Lymphomatoid granulomatosis: a review of 12 cases

We retrospectively studied 12 patients with lymphomatoid granulomatosis (LYG), a form of angiitis and granulomatosis first described in 1972, with emphasis on radiographic findings and clinical presentation. Ten patients had bilateral disease, with middle and lower lung predominance of ill-defined nodular densities being the commonest radiographic presentation. In two patients, chest radiography showed mixed alveolar and interstitial disease. Symptoms of cough, dyspnea, and cutaneous disorders with or without neurologic complications, in a patient with an abnormal chest radiograph, are suggestive of the diagnosis of LYG.