MULTIMODAL IMAGING IN ACUTE RETINAL NECROSIS PRESENTING WITH MACULAR INVOLVEMENT
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Published on: May 26, 2023
Jay C Wang1, Yifan Lu, Lucia Sobrin
1Department of Ophthalmology, Harvard Medical School, Boston, Massachusetts.
Purpose:
To report an unusual case of early macular necrosis in acute retinal necrosis and its features on multimodal imaging.
Methods:
Findings on fundus examination, laboratory workup, fluorescein angiography, autofluorescence, optical coherence tomography, and optical coherence tomography angiography.
Results:
A 31-year-old healthy woman presented with 1 week of photophobia and central scotoma of the right eye. Initial examination revealed vitritis, hyperemia of the optic disc, and a yellow-white macular lesion without any peripheral findings. Peripheral involvement was first noted only 4 days later. The patient was diagnosed with acute retinal necrosis secondary to varicella zoster virus and was successfully treated with intravitreal and oral antiviral medications. Optical coherence tomography imaging of the macular lesion showed involvement of both the inner and outer retina. Optical coherence tomography angiography revealed a large flow void in the choriocapillaris, which has not been previously demonstrated.
Conclusion:
Multimodal imaging offers valuable information in the evaluation of patients with acute retinal necrosis.
