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Human iPSCs Stretch to Improve Tissue-Engineered Vascular Grafts
Nadia O Abutaleb1, George A Truskey1
1Department of Biomedical Engineering, Duke University, Durham, NC 27708, USA.
Cell Stem Cell
|February 8, 2020
Abstract:
Human induced pluripotent stem cells (hiPSCs) provide a potentially unlimited cell source for producing autologous tissue-engineered vascular grafts (TEVGs), which currently suffer from low mechanical strength. In this issue of Cell Stem Cell, Luo et al. (2020) describe optimized culture media and a mechanical stretching regimen to produce hiPSC-derived TEVGs with mechanical behavior similar to that of natural vessels.
