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Trisomy 5 as sole anomaly in acute lymphoblastic leukemia
A A Sandberg1, S S Morgan, R Morgan
1Cancer Center of Southwest Biomedical Research Institute, Scottsdale, AZ 85251.
Cancer Genetics and Cytogenetics
|November 1, 1988
Abstract:
We present a case of B-cell acute lymphoblastic leukemia (ALL) in whose leukemic cells trisomy 5 (+5) was the only cytogenetic anomaly observed. This is the first report of +5 as the sole cytogenetic abnormality in ALL; two cases (one questionable) of acute nonlymphocytic leukemia with such a change have been reported. The findings are presented in relation to other cases with +5 as part of a more complicated cytogenetic picture in hematologic disorders.