Insight Into the Ontogeny of GnRH Neurons From Patients Born Without a Nose

Angela Delaney1,2, Rita Volochayev1,2, Brooke Meader1,2

  • 1Eunice Kennedy Shriver National Institute of Child Health and Human Development, Bethesda, Maryland.

Summary

Congenital arhinia, a condition lacking olfactory structures, reveals that gonadotropin-releasing hormone (GnRH) neurons may not require olfactory pathways for migration or function, challenging previous assumptions about reproductive axis development.

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