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Updated: Dec 29, 2025

Analysis of Lymph Node Volume by Ultra-High-Frequency Ultrasound Imaging in the Braf/Pten Genetically Engineered Mouse Model of Melanoma
Published on: September 8, 2021
Benign tumoral melanosis of a cervical lymph node in a child
Elizabeth F Boscoe1, Mohammad K Hararah1, Mark Lovell2
1Department of Otolaryngology, University of Colorado School of Medicine, 12631 E. 17th Ave., B-205, Aurora, CO, 80045, USA.
Abstract:
We present a pediatric case of benign tumoral melanosis in a cervical lymph node arising from congenital pigmented lesions of the anterior neck. This is the first reported pediatric case not associated with regressed melanoma or trauma. Tumoral melanosis is a rare phenomenon which describes a pigmented lesion like melanoma; however, histology demonstrates melanin-laden macrophages without malignant cells. In the few reported cases, tumoral melanosis has arisen in the skin or lymph node and associated with a regressed melanoma, pigmented basal cell carcinoma or mycosis fungoides. We discuss the pathology of this disease process, and the work up in a pediatric patient.
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