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Preparation and physicochemical properties of uracil derivatives with potential biological activity
P Pecorari1, G Vampa, A Albasini
1Dipartimento di Scienze Farmaceutiche, Università di Modena, Italy.
Il Farmaco; Edizione Scientifica
|April 1, 1988
Abstract:
The characterization of mono- and dimethylated 5-substituted uracils was re-examined. Analysis of their physicochemical properties (pKa, U.V., delta 1H-N.M.R.) affords insight into the structural characteristics of 5-substituted uracil alkylated at the ring nitrogens.