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Updated: Dec 28, 2025

The Unpredictable Chronic Mild Stress Protocol for Inducing Anhedonia in Mice
Published on: October 24, 2018
Anika Pützer1,2, Martin Brüne2,3, Hanns Hatt4
1Department of Cognitive Psychology, Faculty of Psychology, Institute of Cognitive Neuroscience, Ruhr University Bochum, Bochum, Germany.
Hedione, a potential chemosignal, reduced subjective stress when observing others in distress. This olfactory compound did not impact physiological stress or empathic concern, suggesting a specific effect on perceived vicarious stress.
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