Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists01:30

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

456
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
456
Negative and Cognitive Symptoms of Schizophrenia01:30

Negative and Cognitive Symptoms of Schizophrenia

347
Negative symptoms of schizophrenia indicate a reduction or absence of typical behaviors and emotional responses found in healthy individuals, while positive symptoms reflect an excess or distortion of normal functioning.
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
347
Dementia01:30

Dementia

458
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
458
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

701
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
701
Alzheimer's Disease: Overview01:26

Alzheimer's Disease: Overview

1.5K
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
1.5K
Role of Cerebellum and Prefrontal Cortex in Memory01:14

Role of Cerebellum and Prefrontal Cortex in Memory

923
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
923

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The properties of personal semantics.

Memory & cognition·2026
Same author

Brushstrokes of Resilience: The Value of Participating in Arts-Based Research from the Perspective of Older Adults Living with HIV.

Canadian journal on aging = La revue canadienne du vieillissement·2026
Same author

Predictors of cognitive performance in postmenopausal women: findings from the Canadian Longitudinal Study on Aging (CLSA).

Journal of clinical and experimental neuropsychology·2026
Same author

Age and sex differences in cognitive performance in people with subjective cognitive decline and associated worry: Findings from the Canadian Longitudinal Study on Aging.

Journal of neuropsychology·2026
Same author

Assessment and treatment of acquired syntactic deficits: A survey of clinical practice in French speaking populations.

Journal of communication disorders·2026
Same author

'Beyond the Prescription': An Arts-Based Study of Older Adults Living With HIV and Their Primary Care Experiences in Ontario.

Health expectations : an international journal of public participation in health care and health policy·2026
Same journal

Adverse and positive childhood experiences in relation to adolescent mental health: sequential indirect associations.

Frontiers in psychology·2026
Same journal

Personality profiles and usage experience are associated with trust and dependence on generative AI: a latent profile analysis.

Frontiers in psychology·2026
Same journal

Editorial: Promoting replicability: empowering method and applied researchers in driving reliable results.

Frontiers in psychology·2026
Same journal

The mediating roles of the challenge appraisal in the relationship between the coach-athlete relationship and adolescent athletes' burnout.

Frontiers in psychology·2026
Same journal

Unpacking GenAI-enabled deep learning engagement: role perceptions, human-GenAI synergy strategies, and underlying mechanisms.

Frontiers in psychology·2026
Same journal

Violence exposure and cyberbullying among Chinese adolescents: the mediating role of moral disengagement.

Frontiers in psychology·2026
See all related articles

Related Experiment Video

Updated: Dec 28, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.8K

Semantic Function in Mild Cognitive Impairment.

Vanessa Taler1,2, Laura Monetta3,4, Christine Sheppard2

  • 1School of Psychology, University of Ottawa, Ottawa, ON, Canada.

Frontiers in Psychology
|February 11, 2020
PubMed
Summary
This summary is machine-generated.

Semantic deficits in mild cognitive impairment (MCI) are most pronounced in picture naming tasks, indicating issues with lexical access. This suggests picture naming is a key diagnostic tool for identifying MCI-related semantic impairments.

Keywords:
lexical accessmild cognitive impairmentneuropsychological assessmentpicture namingsemantic features

More Related Videos

Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment
08:43

Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment

Published on: August 7, 2017

8.3K
Digital Handwriting Analysis of Characters in Chinese Patients with Mild Cognitive Impairment
05:58

Digital Handwriting Analysis of Characters in Chinese Patients with Mild Cognitive Impairment

Published on: March 11, 2021

5.0K

Related Experiment Videos

Last Updated: Dec 28, 2025

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment
12:18

A Machine Learning Approach to Design an Efficient Selective Screening of Mild Cognitive Impairment

Published on: January 11, 2020

7.8K
Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment
08:43

Application of Granger Causality Analysis of the Directed Functional Connection in Alzheimer's Disease and Mild Cognitive Impairment

Published on: August 7, 2017

8.3K
Digital Handwriting Analysis of Characters in Chinese Patients with Mild Cognitive Impairment
05:58

Digital Handwriting Analysis of Characters in Chinese Patients with Mild Cognitive Impairment

Published on: March 11, 2021

5.0K

Area of Science:

  • Neuropsychology
  • Cognitive Neuroscience

Background:

  • Semantic deficits are a known characteristic of mild cognitive impairment (MCI).
  • The specific nature and extent of these semantic impairments across different cognitive functions are not fully understood.
  • Assessment methods can influence the observed severity of semantic deficits.

Purpose of the Study:

  • To investigate the specific aspects of semantic cognition affected in mild cognitive impairment (MCI).
  • To compare performance on tasks assessing lexical access, retrieval, and recognition of semantic information.
  • To determine the most sensitive tasks for detecting semantic deficits in MCI.

Main Methods:

  • Participants with MCI and cognitively healthy older adults completed a battery of semantic tasks.
  • Tasks varied in input (e.g., visual) and output (e.g., naming) modalities.
  • Performance was analyzed across different semantic processes and item types (biological vs. man-made).

Main Results:

  • Cognitively healthy adults significantly outperformed individuals with MCI across most semantic tasks.
  • The most substantial deficits in the MCI group were observed in picture naming tasks.
  • Deficits were less severe in tasks involving retrieval and recognition of semantic features and associations.
  • Impairment was greater for biological items compared to man-made items in some tasks.

Conclusions:

  • Picture naming tasks are highly sensitive to the semantic deficits associated with mild cognitive impairment (MCI), likely reflecting impaired lexical access.
  • Neuropsychological assessments for MCI should include a comprehensive semantic battery, with picture naming being crucial for identifying deficits.
  • Understanding task-specific impairments aids in characterizing the semantic profile of MCI.