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Targeted Cancer Therapies02:57

Targeted Cancer Therapies

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The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
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Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
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Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
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Related Experiment Video

Updated: Dec 28, 2025

Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence
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Ovarian Cancer Targeted Theranostics.

Sridhar Nimmagadda1,2, Marie-France Penet2,3

  • 1Division of Nuclear Medicine and Molecular Imaging, The Russell H. Morgan Department of Radiology and Radiological Science, The Johns Hopkins University School of Medicine, Baltimore, MD, United States.

Frontiers in Oncology
|February 11, 2020
PubMed
Summary

New theranostic agents offer hope for ovarian cancer patients by combining diagnostic and therapeutic capabilities for early detection and targeted treatment, improving survival rates.

Keywords:
diagnosis and therapymolecular imagingovarian cancertargeted therapytheranostic

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Area of Science:

  • Gynecological Oncology
  • Molecular Imaging
  • Theranostics

Background:

  • Ovarian cancer is a major cause of gynecological cancer death, with poor survival rates when diagnosed late.
  • Advanced-stage ovarian cancer often becomes resistant to conventional treatments, necessitating novel therapeutic strategies.
  • Current diagnostic and treatment methods lack specificity, leading to suboptimal patient outcomes.

Purpose of the Study:

  • To review molecular imaging modalities and targets for ovarian cancer.
  • To explore the development of theranostic agents for improved diagnosis and treatment.
  • To highlight strategies for early detection and targeted therapy delivery in ovarian cancer.

Main Methods:

  • Review of current literature on molecular imaging in ovarian cancer.
  • Analysis of potential molecular targets for imaging and therapy.
  • Discussion of theranostic agent design principles and applications.

Main Results:

  • Various molecular imaging techniques show promise for detecting ovarian cancer.
  • Specific molecular targets are being identified for theranostic agent development.
  • Theranostics offer a dual approach for simultaneous diagnosis and treatment.

Conclusions:

  • Theranostic agents represent a promising frontier for advancing ovarian cancer care.
  • Targeted molecular imaging and therapy can improve early detection and treatment efficacy.
  • Further research into theranostic agents is crucial for enhancing patient survival and quality of life.