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Updated: Dec 28, 2025

Electromagnetic Navigation Transthoracic Nodule Localization for Minimally Invasive Thoracic Surgery
Published on: May 4, 2022
Computed tomography-guided localization for lung nodules: methylene-blue versus coil localization.
Shi-Hang Sun1, Jian Gao1, Xiang-Min Zeng1
1Department of Medical Imaging, Yidu Central Hospital, Weifang Medical University, Qingzhou, Shandong, China.
Both computed tomography (CT)-guided methylene-blue (MB) and coil localization are effective for lung nodule (LN) resection. Coil localization allows for a longer delay between the procedure and surgery compared to MB.
Area of Science:
- Thoracic Surgery
- Medical Imaging
- Pulmonology
Background:
- Lung nodules (LNs) require precise localization for effective surgical resection.
- Preoperative localization techniques aim to improve the success rates of minimally invasive procedures like video-assisted thoracoscopic surgery (VATS).
Purpose of the Study:
- To compare the clinical efficacy of CT-guided methylene-blue (MB) versus coil localization for lung nodules (LNs).
- To evaluate the technical success rates of localization and subsequent VATS-guided wedge resection for both methods.
Main Methods:
- A retrospective study of 89 patients with LNs undergoing CT-guided MB or coil localization followed by VATS wedge resection.
- Comparison of technical success rates for localization and resection between the MB and coil groups.
Main Results:
- Both MB and coil localization demonstrated high success rates: 97.9% for MB and 96.9% for coil localization and wedge resection.
- No significant differences in technical success were observed between the two groups (p=1.000).
- The coil group had a significantly longer interval between localization and VATS (14.4 hours) compared to the MB group (1.6 hours) (p=0.001).
Conclusions:
- CT-guided MB and coil localization are safe and effective for achieving high success rates in VATS-guided wedge resection of LNs.
- Coil localization offers greater flexibility due to a potentially longer time interval before VATS compared to MB localization.
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