Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Decision-Making Criteria in Polygenic Embryo Screening: A Survey of Reproductive Medicine Physicians.

Genetics in medicine : official journal of the American College of Medical Genetics·2026
Same author

Taking actuarial fairness seriously: what is required for the ethical use of genetics in insurance?

Journal of law and the biosciences·2026
Same author

Engaging patient communities in intracranial neuroscience research.

medRxiv : the preprint server for health sciences·2026
Same author

Comparison of neuropsychological side effects between contemporary radiofrequency ablative neurosurgery for psychiatric disorders and conventional neurosurgical procedures: systematic review and meta-analysis.

Journal of neurology, neurosurgery, and psychiatry·2026
Same author

Proceedings of the 13th annual deep brain stimulation think tank: the evolving landscape.

Frontiers in human neuroscience·2026
Same author

Views and experiences regarding workplace genetic testing: findings from a national survey of U.S. employees.

Journal of community genetics·2026
Same journal

Who Receives Ethics Consultations? An Analysis of Racial and Ethnic Characteristics of an Ethics Consult Service in an Urban Academic Medical Center.

AJOB empirical bioethics·2026
Same journal

"I Have Someone's Life in my Hands": How Cancer Care Partners Experience and Navigate Moral Challenges.

AJOB empirical bioethics·2026
Same journal

"It's an Uphill Battle. We Have a Long Way to Go": Perspectives of Canadian Individuals Living with Genetic Conditions Detectable by Prenatal Cell-Free DNA Screening.

AJOB empirical bioethics·2026
Same journal

Psychological Harms of HIV Vaccine Trial Participation in Tanzania: Could Post-Trial Participants Engagement Help?

AJOB empirical bioethics·2026
Same journal

Canadian Medical Assistance in Dying (MAID) and Access to Resources: An Analysis of Media Reports.

AJOB empirical bioethics·2026
Same journal

Do Reasons Matter? An Empirical Exploration of the Role of Parents' Reasons in Treatment Refusal in Pediatric Oncology.

AJOB empirical bioethics·2026
See all related articles

Related Experiment Video

Updated: Dec 28, 2025

Author Spotlight: Real-Time Imaging of Bonding in 3D-Printed Layers
04:36

Author Spotlight: Real-Time Imaging of Bonding in 3D-Printed Layers

Published on: September 1, 2023

3.8K

Is Real-Time ELSI Realistic?

John M Conley1, Anya E R Prince2, Arlene M Davis3

  • 1School of Law, University of North Carolina.

AJOB Empirical Bioethics
|February 11, 2020
PubMed
Summary
This summary is machine-generated.

Integrating ethical, legal, and social implications (ELSI) into genomics research in real time presents challenges. While ELSI researchers were included, their influence on the project

Keywords:
Public healthbiomedical researchclinical geneticsgenetic research

More Related Videos

Real-Time, Two-Color Stimulated Raman Scattering Imaging of Mouse Brain for Tissue Diagnosis
10:57

Real-Time, Two-Color Stimulated Raman Scattering Imaging of Mouse Brain for Tissue Diagnosis

Published on: February 1, 2022

3.5K
Author Spotlight: Image-Based Methods to Study Membrane Trafficking Events in Stomatal Lineage Cells
11:31

Author Spotlight: Image-Based Methods to Study Membrane Trafficking Events in Stomatal Lineage Cells

Published on: May 12, 2023

1.5K

Related Experiment Videos

Last Updated: Dec 28, 2025

Author Spotlight: Real-Time Imaging of Bonding in 3D-Printed Layers
04:36

Author Spotlight: Real-Time Imaging of Bonding in 3D-Printed Layers

Published on: September 1, 2023

3.8K
Real-Time, Two-Color Stimulated Raman Scattering Imaging of Mouse Brain for Tissue Diagnosis
10:57

Real-Time, Two-Color Stimulated Raman Scattering Imaging of Mouse Brain for Tissue Diagnosis

Published on: February 1, 2022

3.5K
Author Spotlight: Image-Based Methods to Study Membrane Trafficking Events in Stomatal Lineage Cells
11:31

Author Spotlight: Image-Based Methods to Study Membrane Trafficking Events in Stomatal Lineage Cells

Published on: May 12, 2023

1.5K

Area of Science:

  • Genomics
  • Bioethics
  • Public Health

Background:

  • Growing skepticism exists regarding the ability of cutting-edge scientific research to address ethical and policy considerations in real time.
  • The question arises whether Ethical, Legal, and Social Implications (ELSI) can contribute to genomics proactively or remain an after-the-fact critique.
  • This study examines real-time ELSI integration within a genomic screening project (GeneScreen) from inception to completion.

Purpose of the Study:

  • To assess the effectiveness and influence of embedded, real-time Ethical, Legal, and Social Implications (ELSI) researchers in a genomic screening project.
  • To determine if ELSI can be integrated proactively into genomics research or if it remains a reactive function.

Main Methods:

  • Employed reflexive ethnography as part of the study design, involving participant observation.
  • Researchers actively participated in task-oriented groups, recorded meetings, and conducted qualitative analysis.
  • Conducted and analyzed post-project interviews with multiple participants.

Main Results:

  • The real-time ELSI initiative yielded mixed results, with a largely positive assessment regarding ELSI researchers' participation and ability to voice concerns.
  • Instances where ELSI contributions significantly altered the project's direction or confirmed the status quo were limited.
  • ELSI researchers were often perceived as 'tolerated guests' rather than integral decision-makers.

Conclusions:

  • Significant barriers hinder real-time ELSI influence in genomic research.
  • Challenges stem from knowledge disparities, epistemological biases, and time/financial pressures inherent in genomic research, not intentional exclusion.
  • Proactive ELSI integration requires addressing these systemic factors within research frameworks.