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Published on: October 28, 2020
Diagnostic utility of the electrocardiographic left ventricular hypertrophy criteria in specific populations
Fernando De la Garza Salazar1,2, Elías Abraham Rodríguez Díaz1,3, Arnulfo González Cantú4
1Universidad de Monterrey, Mexico.
Insights
The Dalfó electrocardiogram (ECG) criterion is most accurate for detecting left ventricular hypertrophy (LVH) in Northern Mexican populations. This finding is crucial for improving LVH diagnosis in diverse ethnic groups.
Area of Science:
- Cardiology
- Medical Diagnostics
- Electrocardiography
Background:
- Established electrocardiogram (ECG) criteria for left ventricular hypertrophy (LVH) diagnosis are primarily validated in Caucasian populations.
- The diagnostic utility of these ECG criteria in non-Caucasian populations, specifically Northern Mexicans, remains unestablished.
- Despite this, existing ECG criteria are frequently applied in clinical practice for LVH detection.
Purpose of the Study:
- To assess the diagnostic performance of various ECG criteria for identifying LVH in a Northern Mexican cohort.
- To investigate the influence of demographic and clinical factors (gender, age, BMI, hypertension, IHD) on the accuracy of these ECG criteria.
Main Methods:
- An observational, case-control study design was employed.
- Patients were categorized based on echocardiogram (Echo) confirmation of LVH.
- The diagnostic accuracy, sensitivity, specificity, PPV, and NPV of 22 distinct ECG criteria were calculated.
Main Results:
- The Dalfó criterion (SV3 + RaVL) demonstrated the highest overall diagnostic accuracy (64.1%) in the study population.
- This criterion exhibited superior performance across various subgroups, including both genders, all BMI categories, older adults (>60 years), and patients with positive Echo-ischemic heart disease (IHD).
- The VDP Cornell criterion showed the best accuracy in younger patients (<60 years) and those with non-ischemic findings on Echo.
Conclusions:
- The Dalfó criterion emerged as the most accurate ECG method for detecting LVH in the studied Northern Mexican population.
- Its effectiveness extends to specific demographic and clinical subgroups, highlighting its broad applicability.
- These findings support the use of the Dalfó criterion for more reliable LVH diagnosis in this population.
Background:
Several electrocardiographic (ECG) criteria have been validated for the diagnosis of left ventricular hypertrophy (LVH); the majority in Caucasian subjects from Europe and North America. Diagnostic utility of ECG criteria to detect LVH has never been established in our population; nonetheless they are frequently used.
Objective:
To evaluate the diagnostic utility of different LVH ECG criteria in a Northern Mexican population and to determine the effect of gender, age, body mass index (BMI), hypertension and ischaemic heart disease (IHD) on their performance.
Methods:
We conducted an observational, case-control study in patients divided according to the presence of LVH in an echocardiogram (Echo). We calculated the accuracy, sensitivity (Se), specificity (Sp), positive predictive value (PPV) and negative predictive value (NPV) of 22 ECG criteria.
Results:
Four hundred thirty-two patients were studied (202 had LVH). The Dalfó criterion (ECG18. SV3 + RaVL) had the best diagnostic performance with a Se of 56%, Sp of 71.3%, PPV 62.9%, NPV 65% and a diagnostic accuracy (95%CI) of 64.1% (59.5-68.6). This criterion had the highest accuracy in both genders, in all BMI, in older patients (>60 years) and in those with positive Echo ischaemic heart disease (IHD); it also performed well in patients with history of IHD and in hypertensive patients. VDP Cornell had the best accuracy in patients less than 60 years old, and in patients with non-ischaemic findings by Echo.
Conclusions:
The Dalfó criteria had the overall best accuracy in the detection of LVH, and specific populations.
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