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Related Experiment Video

Updated: Dec 28, 2025

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

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Normal tissue sparing using different techniques for prostate irradiation.

Barbara Melles-Bencsik1, Tamás Pócza1, Tibor Major1

  • 1Radiotherapy Centre, National Institute of Oncology, Budapest, Hungary.

Reports of Practical Oncology and Radiotherapy : Journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology
|February 12, 2020
PubMed
Summary

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CBCT based online daily adaptive treatment improves target coverage with limited benefit for OAR protection in SBRT prostate cancer.

Radiation oncology (London, England)·2026
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Patient selection for accelerated partial breast irradiation (APBI) after breast-conserving surgery: Updated evidence-based recommendations of the Groupe Européen de Curiethérapie-European Society for Therapeutic Radiology and Oncology (GEC-ESTRO) Breast Cancer Working Group.

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Correction: Jalloul et al. Targeted Alpha Therapy: Exploring the Clinical Insights into [225Ac]Ac-PSMA and Its Relevance Compared with [177Lu]Lu-PSMA in Advanced Prostate Cancer Management. <i>Pharmaceuticals</i> 2025, <i>18</i>, 1215.

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In Regard to Facondo et al.

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[History of Hungarian radiotherapy - from radium needles to the CyberKnife].

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Magyar onkologia·2026

This study compared radiation techniques for prostate cancer, finding RapidArc offers similar or better normal tissue sparing than conventional methods. Simultaneously Integrated Boost (SIB) provided comparable sparing to conventional fractionation with RapidArc.

Area of Science:

  • Radiation Oncology
  • Medical Physics

Background:

  • Dose escalation in prostate cancer (PCa) improves outcomes but necessitates careful normal tissue sparing.
  • Optimizing radiation techniques is crucial for reducing dose to surrounding organs-at-risk (OARs).

Purpose of the Study:

  • To evaluate normal tissue sparing using dosimetric parameters across different irradiation techniques for conventional (CFRT) and simultaneously integrated boost (SIB) schedules.
  • To compare RapidArc (RA), Sliding Window (SW) IMRT, and 4-field box (3D-CRT) in sparing pelvic normal tissues.

Main Methods:

  • Treatment plans were generated for 15 high-risk prostate cancer patients using RA, SW IMRT, and 3D-CRT.
  • Pelvic normal tissue volumes were analyzed using six concentric cylindrical structures with 1 cm wall thickness.
Keywords:
Normal tissue sparingProstate cancerRadiotherapySimultaneously integrated boost

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Main Results:

  • All techniques achieved target coverage (V95%>95%).
  • 3D-CRT showed inferior sparing for the rectum and bilateral femoral heads compared to RA and SW IMRT.
  • RapidArc (RA) demonstrated increased low-dose (V5-V15) sparing but decreased high-dose (V20, V30) sparing compared to other techniques.

Conclusions:

  • RapidArc (RA) provides comparable or superior normal tissue sparing in prostate cancer radiotherapy.
  • Simultaneously Integrated Boost (SIB) schedules achieve similar normal tissue sparing to conventional fractionation when planned with RapidArc.