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Related Experiment Video

Updated: Dec 28, 2025

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
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Nanoparticle-based Cell Trackers for Biomedical Applications.

Jen-Shyang Ni1,2, Yaxi Li1,3, Wentong Yue1

  • 1Department of Biomedical Engineering, Academy for Advanced Interdisciplinary Studies, Southern University of Science and Technology, Shenzhen, Guangdong 518055, China.

Theranostics
|February 12, 2020
PubMed
Summary
This summary is machine-generated.

Biocompatible nanoparticles enable real-time tracking of biological processes for diagnosis and treatment. This review covers nanoparticle cell trackers for advanced imaging and therapeutic applications.

Keywords:
aggregation-induced emissionbioimagingcell trackingsemiconducting polymertherapy

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Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Medical Imaging

Background:

  • Continuous tracking of biological processes is crucial for accurate diagnosis and treatment.
  • Nanoparticles offer promising solutions for real-time monitoring in areas like cancer metastasis and tissue regeneration.

Purpose of the Study:

  • To review the development and applications of various nanoparticle-based cell trackers.
  • To explore their use in diverse imaging technologies and therapeutic strategies.

Main Methods:

  • Review of aggregation-induced emission (AIE) dots, quantum dots (QDs), nanodiamonds, superparamagnetic iron oxide nanoparticles (SPIONs), and semiconducting polymer nanoparticles (SPNs).
  • Discussion of applications in fluorescence imaging, photoacoustic imaging, magnetic resonance imaging, magnetic particle imaging, positron emission tomography, and single photon emission computed tomography.

Main Results:

  • Detailed examination of nanoparticle-based cell trackers for various imaging modalities.
  • Introduction of multi-functional trackers with photodynamic and photothermal therapeutic capabilities.

Conclusions:

  • Nanoparticle trackers are vital for precise diagnosis, treatment monitoring, and advanced biomedical imaging.
  • The integration of therapeutic modalities with tracking offers a comprehensive approach to disease management.