Fatal eosinophilic coronary periarteritis leads to dissection in a young patient: A case report

Eosinophilic coronary periarteritis (ECPA) is a poorly studied type of coronary arteritis. It causes myocardial ischemia and most cases are diagnosed at autopsy. We report the case of a 35-year-old woman who presented with sudden unexpected cardiac arrest and was brought to the emergency ward. Cardiopulmonary resuscitation was started by ambulance paramedic. On arrival, the patient was transferred to the catheterization laboratory due to sudden aborted cardiac death. The angiography was performed and dissection of the left main coronary artery, extended to the left anterior descending artery was detected. Pathological study confirmed ECPA. It appears that young and healthy patients with a history of intermittent vasospastic angina should be evaluated for ECPA. <Learning objective: Young and healthy patients with a history of intermittent Prinzmetal vasospastic angina should be evaluated for eosinophilic coronary periarteritis (ECPA) prior to sudden cardiac death. Since ECPA is an unexpected and life-threatening condition, developing a diagnostic tool amongst suspicious young and healthy patients is demanded. Positron emission tomography-computed tomography might be an interesting tool, since it can detect infiltrative cells in early stages of cardiac inflammatory disease.>.