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Updated: Dec 28, 2025

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction
Published on: June 29, 2013
Importance of Follow-Up and Early Detailed Evaluation in Early Onset Growth Restricted Fetuses
M Miescu1,2, O Carbunaru3, C Constantin1,2
1Department of Obstetrics and Gynecology, University of Medicine and Pharmacy of Craiova.
Insights
Early onset fetal growth restriction (EO-FGR) requires careful first-trimester diagnosis. This case highlights how detailed ultrasound follow-up aids in managing EO-FGR and triploidy with unusual features.
Area of Science:
- Perinatology
- Medical Imaging
- Genetics
Background:
- Early onset fetal growth restriction (EO-FGR) presents significant risks to both fetus and mother, necessitating accurate diagnosis and management.
- First-trimester fetal anomaly screening can be challenging due to fetal position and the small size of developing structures, potentially limiting diagnostic clarity.
Observation:
- This case report details the diagnostic journey of a fetus with EO-FGR and triploidy, exhibiting atypical ultrasound features.
- Challenges in first-trimester imaging were overcome through meticulous ultrasound scan follow-up.
- Both transabdominal and transvaginal ultrasound approaches were employed for comprehensive structural evaluation.
Findings:
- Detailed ultrasound follow-up enabled a thorough structural assessment, crucial for diagnosis and prognosis.
- The combined imaging techniques facilitated the identification of EO-FGR and atypical triploidy features in the first trimester.
- Accurate diagnosis was achieved despite initial imaging limitations.
Implications:
- This case underscores the importance of persistent and detailed ultrasound evaluation in managing complex first-trimester pregnancies.
- Improved diagnostic accuracy for EO-FGR and chromosomal abnormalities like triploidy can lead to better pregnancy outcomes and management strategies.
- The findings support the utility of advanced ultrasound techniques in overcoming limitations in early fetal anomaly detection.
Abstract:
Early onset fetal growth restriction (EO-FGR) is associated with significant feto-maternal complications, therefore efforts should be made to identify the causes and the potential outcome of the pregnancy. Some of the pitfalls in first-trimester imaging of the fetal anomalies are related to the inadequacy of the examination, because of the fetal position and limited clarity in relation to the size of the structures being examined. In this paper we present a case where careful ultrasound scan follow-up and the use of both approaches transabdominal and transvaginal were useful to complete a detailed structural evaluation as part of the diagnosis, management and prognosis of a fetuses diagnosed with EO-FGR in the first trimester and a triploidy with atypical ultrasound features.

