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The Integrative Migraine Pain Alleviation through Chiropractic Therapy (IMPACT) trial: Study rationale, design and
P M Wayne1,2, C Bernstein3,4, M Kowalski4
1Osher Center for Integrative Medicine, Harvard Medical School and Brigham and Women's Hospital, Boston, MA, USA.
Contemporary Clinical Trials Communications
|February 12, 2020
Summary
This pilot study explored chiropractic care for episodic migraine in women. Findings will guide a larger trial on this non-pharmacological approach for migraine relief.
Area of Science:
- Neurology
- Integrative Medicine
- Musculoskeletal Health
Background:
- Migraine affects 15% of the US population, disproportionately impacting women.
- Many individuals with migraine seek complementary and integrative medicine (CIM).
- Chiropractic care is a promising non-pharmacological option for migraine management.
Purpose of the Study:
- To evaluate the safety and feasibility of a multimodal chiropractic care intervention for episodic migraine.
- To gather preliminary data on chiropractic care's effectiveness for migraine frequency, severity, duration, and medication use.
- To assess chiropractic care's impact on disability, quality of life, and psychosocial well-being in women with migraine.
Main Methods:
- The Integrative Migraine Pain Alleviation through Chiropractic Therapy (IMPACT) study is a pilot pragmatic randomized clinical trial.
- 60 adult women (20-55 years) with episodic migraine were randomized.
- Intervention: Multimodal chiropractic care (10 sessions/14 weeks) plus enhanced usual care (UC) vs. enhanced UC alone.
Main Results:
- Preliminary data on effectiveness for migraine frequency, severity, duration, and medication use will be provided.
- Preliminary estimates of effects on disability, quality of life, and psychosocial well-being will be reported.
- Safety and feasibility of the study design will be determined.
Conclusions:
- Findings will inform the design of a full-scale trial.
- This study investigates chiropractic care as a potential non-pharmacological treatment for episodic migraine in women.
