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Single Anastomosis Duodenal Switch: 1-Year Outcomes
Daniel Cottam1, Mitchell Roslin2, Paul Enochs3
1Bariatric Medicine Institute, 1046 E 100 S, Salt Lake City, UT, 84102, USA. drdanielcottam@yahoo.com.
Obesity Surgery
|February 12, 2020
Summary
Single-anastomosis duodenal switch (SADS) is an effective bariatric surgery for significant weight loss and comorbidity resolution. While generally safe, potential vitamin and mineral deficits require long-term monitoring.
Area of Science:
- Bariatric Surgery
- Metabolic Surgery
- Gastroenterology
Background:
- Single-anastomosis duodenal switch (SADS) is a bariatric procedure proposed for effective weight loss.
- It may reduce micronutrient deficiencies by lengthening the common channel.
Purpose of the Study:
- To evaluate weight loss, comorbidity resolution, and 1-year nutritional outcomes of the SADS procedure.
Main Methods:
- 120 patients underwent SADS across six US sites from October 2014 to January 2017.
- Weight loss, comorbidities, quality of life, and adverse events were monitored for 12 months.
- Follow-up assessments were conducted at 1, 6, and 12 months post-procedure.
Main Results:
- Significant BMI reduction from 46.8 to 29.8 at 12 months (P < 0.001).
- 96.3% of type 2 diabetes patients achieved resolution by 12 months, with mean A1C reduction.
- Improvements noted in hyperlipidemia, sleep apnea, hypertension, and quality of life scores; normal protein levels; abnormal parathyroid hormone and vitamin D.
Conclusions:
- SADS is highly efficacious for weight loss and significant comorbidity reduction within 1 year.
- Complications and nutritional deficits at 1 year are comparable to other malabsorptive procedures.
- Long-term follow-up is crucial for monitoring complications and potential vitamin/mineral deficiencies.

