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Antitumor principles in mosses: the first isolation and identification of maytansinoids, including a novel
K Sakai1, T Ichikawa, K Yamada
1Sagami Chemical Research Center, Kanagawa, Japan.
Journal of Natural Products
|September 1, 1988
Abstract:
A novel 15-methoxyansamitocin P-3 [2], in company with three known maytansinoids 1, 3, and 4, was isolated for the first time from two Japanese mosses, Isothecium subdiversiforme and Thamnobryum sandei. All are potent cytotoxic compounds.