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Right ventricular diastolic dysfunction in patients with obstructive sleep apnea syndrome
Junfang Li1, Xiaotong Lin2, Huichao Li3
1Department of Echocardiography, The Affiliated Hospital of Qingdao University, Qingdao, China.
Echocardiography (Mount Kisco, N.Y.)
|February 12, 2020
Summary
Right ventricular diastolic dysfunction in obstructive sleep apnea syndrome (OSAS) is detectable with velocity vector imaging (VVI). RV-SRe measurements correlate with disease severity, indicating early myocardial changes.
Area of Science:
- Cardiology
- Sleep Medicine
- Medical Imaging
Background:
- Obstructive sleep apnea syndrome (OSAS) is linked to cardiovascular complications.
- Right ventricular (RV) diastolic dysfunction can precede heart failure and pulmonary hypertension in OSAS patients.
Purpose of the Study:
- To assess RV diastolic dysfunction in OSAS patients using velocity vector imaging (VVI).
- To evaluate the efficacy of VVI technology in diagnosing RV diastolic dysfunction in OSAS.
Main Methods:
- 69 OSAS patients (mild, moderate, severe based on AHI) and 35 controls were enrolled.
- VVI was used to acquire digital images of apex four-chamber views.
- Measurements included peak early diastolic strain rate (RV-SRe) and late diastolic strain rate (RV-SRa).
Main Results:
- RV-SRe, RV-SRa, and their ratio decreased with increasing OSAS severity.
- Moderate and severe OSAS groups showed significantly lower RV-SRe and RV-SRe/RV-SRa compared to controls and mild OSAS.
- RV-SRe demonstrated the strongest correlation with the apnea-hypopnea index (AHI).
Conclusions:
- RV diastolic dysfunction is an early manifestation in OSAS patients.
- VVI, particularly RV-SRe, can detect subclinical myocardial dysfunction and reflect RV diastolic dysfunction effectively.
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