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Radiation induced lichen planus - an uncommon side effect.

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Radiation therapy for prostate cancer can rarely cause lichen planus, a skin condition. This case highlights radiation as a potential trigger for lichen planus, even without prior history.

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Area of Science:

  • Dermatology
  • Oncology
  • Radiation Oncology

Background:

  • Cutaneous lichen planus typically presents as pruritic, violaceous papules and plaques on the extremities.
  • Lichen planus developing after radiation therapy is rare.
  • No prior reports exist of lichen planus following radiation for prostate carcinoma.

Observation:

  • A 66-year-old man developed a symmetric, pruritic eruption in the pelvic and gluteal region two months post-radiation therapy for prostate adenocarcinoma.
  • The eruption presented as well-demarcated, violaceous papules and plaques in a band-like distribution.
  • Histopathology confirmed hypertrophic lichen planus with characteristic epidermal and dermal changes.

Findings:

  • Radiation therapy for prostate cancer can induce lichen planus.
  • This represents a novel association in medical literature.
  • The condition manifested as hypertrophic lichen planus.

Implications:

  • Clinicians should consider radiation therapy as a potential risk factor for developing lichen planus.
  • Recognition of this association is crucial for accurate diagnosis and management.
  • Further research may elucidate the mechanisms linking radiation and lichen planus development.