Related Experiment Video
Updated: Dec 28, 2025
07:05
In Vitro Evaluation of The Effects Of Er,Cr:YSGG and Diode Lasers Used on Titanium Cylinder
Published on: June 6, 2025
415
Er,Cr:YSGG Laser Performance Improves Biological Response on Titanium Surfaces
Wan-Ling Yao1, Jerry Chin Yi Lin1, Eisner Salamanca1
1School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan.
Materials (Basel, Switzerland)
|February 13, 2020
Summary
Erbium, chromium-doped yttrium scandium gallium garnet (Er,Cr:YSGG) laser treatment smoothed titanium implant surfaces, reducing Porphyromonas gingivalis adhesion and bacterial colonization. This laser therapy enhanced fibroblast viability and osteoblast differentiation, offering a promising approach for managing peri-implantitis.
Area of Science:
- Biomaterials Science
- Dental Implantology
- Microbiology
Background:
- Porphyromonas gingivalis infection is a key factor in dental implant failures, often leading to peri-implantitis.
- Implant surface roughness significantly influences P. gingivalis adhesion, exacerbating peri-implantitis and subsequent cell adhesion.
- Effective management strategies are crucial to prevent implant failure and address peri-implantitis.
Purpose of the Study:
- To investigate the impact of Er,Cr:YSGG laser treatment on titanium (Ti) disc surfaces.
- To evaluate the effects of laser treatment on P. gingivalis adhesion and fibroblast viability.
- To assess the potential of Er,Cr:YSGG laser as an adjunctive therapy for peri-implantitis management.
Main Methods:
- Titanium discs were treated with either autoclaving (control) or Er,Cr:YSGG laser (test).
- Surface characteristics were analyzed using SEM, EDX, and XPS; surface roughness and wettability were measured.
- Bacterial adhesion, fibroblast viability (WST-1 assay), and osteoblast differentiation (ALP assay) were assessed.
Main Results:
- Er,Cr:YSGG laser treatment resulted in smoother Ti surfaces compared to controls (0.25-µm decrease in roughness, p < 0.05).
- Laser-treated discs exhibited significantly reduced P. gingivalis adhesion (p < 0.01) and colonization (p < 0.05).
- Fibroblast viability and osteoblast differentiation were notably increased on laser-treated surfaces (p < 0.05).
Conclusions:
- Er,Cr:YSGG laser treatment effectively modifies titanium surfaces, reducing bacterial adhesion and promoting cellular responses.
- The observed reduction in P. gingivalis adhesion and enhanced cell viability suggest potential benefits for peri-implantitis management.
- Laser-assisted therapy warrants further investigation for developing improved clinical guidelines for peri-implantitis treatment.
