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Pericardial Sarcoma: "Invisible" on Radiology.
Cheng Wei1, Boxuan Hu1, Xiaofan Peng1
1Department of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, Hunan, China.
The Canadian Journal of Cardiology
|February 13, 2020
Summary
Primary pericardial fibrosarcoma is a rare, aggressive cancer presenting as recurrent hemorrhagic pericardial effusion. Advanced imaging may miss this rare tumor, highlighting its importance in differential diagnosis.
Area of Science:
- Cardiology
- Oncology
- Radiology
Background:
- Primary pericardial tumors are exceptionally rare and aggressive carcinomas.
- Recurrent hemorrhagic pericardial effusion is the primary presenting symptom.
Observation:
- A 17-year-old patient presented with recurrent hemorrhagic pericardial effusion.
- Despite advanced imaging (CT, FDG-PET-CT), no tumor was detected, only fluid.
- The patient was diagnosed with primary pericardial fibrosarcoma.
Findings:
- This case highlights the diagnostic challenges of primary pericardial fibrosarcoma.
- Radiological examinations can be inconclusive in identifying these rare tumors.
- Recurrent hemorrhagic pericardial effusions warrant consideration of pericardial tumors in the differential diagnosis.
Implications:
- Emphasizes the need for high clinical suspicion for rare pericardial tumors.
- Suggests limitations of current imaging modalities in detecting early-stage or subtle pericardial fibrosarcoma.
- Underscores the importance of integrating clinical presentation with imaging findings for accurate diagnosis.

