Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association between ovarian reserve and utilization of preimplantation genetic testing for aneuploidy in autologous IVF cycles.

Human reproduction open·2026
Same author

Size matters: breaking the decades-old dogma of universal follicle size for timing egg retrieval.

Reproductive biomedicine online·2026
Same author

Re-evaluating endometrial injury for IVF: was a promising approach abandoned prematurely? A critical review.

Reproductive biomedicine online·2026
Same author

Reclaiming 'abnormal' embryos after preimplantation genetic testing for aneuploidy: patients' perspectives on transferring embryos against prior institutional advice.

Human reproduction open·2026
Same author

Incidental endometrial cancer diagnosis during pre-IVF workup: fertility-sparing treatment and embryo preservation.

JCEM case reports·2026
Same author

Recurrent Second-Trimester Euploid Pregnancy Loss Associated With Maternal-Paternal HLA Compatibility: Review Based on a Case Report of Immune-Mediated Failure.

American journal of reproductive immunology (New York, N.Y. : 1989)·2026

Related Experiment Video

Updated: Dec 28, 2025

Morphometric Protocol for the Objective Assessment of Blastocyst Behavior During Vitrification and Warming Steps
08:28

Morphometric Protocol for the Objective Assessment of Blastocyst Behavior During Vitrification and Warming Steps

Published on: February 28, 2019

9.2K

Is Embryo Cryopreservation Causing Macrosomia-and What Else?

Raoul Orvieto1,2, Michal Kirshenbaum1, Norbert Gleicher3,4,5

  • 1Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Ramat Gan, Israel.

Frontiers in Endocrinology
|February 13, 2020
PubMed
Summary
This summary is machine-generated.

Single embryo transfer strategies, including frozen-thawed embryo transfer (FET), reduce multiple births. However, FET may increase risks of fetal macrosomia, hypertensive disorders, and perinatal mortality compared to fresh embryo transfer.

Keywords:
IVFcryopreservationfrozen-thawed embryo transfermacrosomiapregnancy complications

More Related Videos

Cryopreservation of Preimplantation Embryos of Cattle, Sheep, and Goats
11:10

Cryopreservation of Preimplantation Embryos of Cattle, Sheep, and Goats

Published on: August 5, 2011

31.2K
Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts
09:35

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts

Published on: March 2, 2017

12.3K

Related Experiment Videos

Last Updated: Dec 28, 2025

Morphometric Protocol for the Objective Assessment of Blastocyst Behavior During Vitrification and Warming Steps
08:28

Morphometric Protocol for the Objective Assessment of Blastocyst Behavior During Vitrification and Warming Steps

Published on: February 28, 2019

9.2K
Cryopreservation of Preimplantation Embryos of Cattle, Sheep, and Goats
11:10

Cryopreservation of Preimplantation Embryos of Cattle, Sheep, and Goats

Published on: August 5, 2011

31.2K
Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts
09:35

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts

Published on: March 2, 2017

12.3K

Area of Science:

  • Reproductive Medicine and Perinatology

Background:

  • High incidence of multiple births in IVF is linked to perinatal morbidity.
  • Single embryo transfer (SET) strategies, including fresh embryo transfer (ET) and frozen-thawed embryo transfer (FET), aim to reduce multiple births and associated complications.

Purpose of the Study:

  • To assess obstetrics and perinatal outcomes of FET compared to fresh ET and natural conception.
  • To inform decision-making regarding elective freeze-all policies in IVF.

Main Methods:

  • Literature review of available evidence comparing FET, fresh ET, and natural conception.
  • Analysis of obstetrics and perinatal outcomes, including birth weight, gestational age, and mortality.

Main Results:

  • FET associated with lower risk of prematurity and low birth weight in singletons compared to fresh ET.
  • FET linked to increased risk of large for gestational age (LGA)/macrosomia, hypertensive disorders of pregnancy, and perinatal mortality.
  • Conflicting results for pregnancy rates in normal responders comparing fresh ET and FET.

Conclusions:

  • While FET reduces multiple births, it may increase risks of specific pregnancy complications.
  • Elective freeze-all policies should consider increased risks of LGA/macrosomia, hypertensive disorders, and perinatal mortality alongside live birth rates and OHSS risk.