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How Should Biobanking Be Governed in Low-Resource Settings?
Aminu Yakubu, Nchangwi Syntia Munung, Jantina De Vries1
1An associate professor of bioethics in the Department of Medicine at the University of Cape Town in South Africa.
AMA Journal of Ethics
|February 13, 2020
Summary
Developing biobanks in Africa presents ethical challenges. A comprehensive governance framework is proposed to ensure African leadership and address issues like informed consent and benefit sharing in cancer research.
Area of Science:
- Biobanking
- Cancer Research
- African Health Systems
Background:
- Biobank development in Africa faces unique ethical considerations.
- Underresourced healthcare and research infrastructures are prevalent.
- Low average research literacy impacts ethical engagement.
Purpose of the Study:
- To describe ethical challenges in African biobanking.
- To propose solutions for navigating these challenges.
- To promote African leadership in biobanking research.
Main Methods:
- Ethical analysis of biobanking contexts in Africa.
- Review of challenges in informed consent, benefit sharing, and stigmatization.
- Proposal for a comprehensive governance framework.
Main Results:
- Informed consent, benefit sharing, and stigmatization are key ethical challenges.
- Existing infrastructures and literacy levels complicate biobanking ethics.
- A governance framework is essential for ethical biobanking.
Conclusions:
- Addressing ethical challenges is crucial for successful biobanking in Africa.
- African leadership in governance frameworks is vital.
- Comprehensive frameworks can ensure ethical conduct and equitable benefit sharing.
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