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Updated: Dec 28, 2025

Probing the Structure and Dynamics of Interfacial Water with Scanning Tunneling Microscopy and Spectroscopy
Published on: May 27, 2018
Photoinduced interruption of interannular cooperativity for delivery of cationic guests in water
Radoslav Z Pavlović1, Sarah E Border1, Yiming Li2
1Department of Chemistry & Biochemistry, The Ohio State University, 100 West 18th Avenue, Columbus 43210, OH, USA. badjic.1@osu.edu.
Abstract:
The synergy among twelve carboxylates from two hexavalent baskets 16- assisted the encapsulation of one divalent diammonium guest 32+-62+ and the formation of ternary [3-6⊂12]10-. The reduction of basket's multivalency, by photoinduced α-decarboxylation of 16- to give 23-, intercepted the interannular cooperativity operating in the stabilization of capsulpex [3-6⊂12]10- to dramatically diminish the binding affinity towards diammonium guests. As a result, the cationic guests were released into bulk water with 23- assembling into nanoparticles. With numerous drugs carrying positive sites, the finding reported here could now be examined for their light-promoted spatiotemporal delivery.
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