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Area of Science:

  • Anatomy
  • Physiology
  • Urology

Background:

  • The precise structure and function of the prostate's longitudinal muscular column (LMC) remain unclear.
  • Understanding the LMC is crucial for elucidating the mechanics of ejaculation.

Purpose of the Study:

  • To investigate the form and muscular arrangement of the LMC in the posterior wall of the prostatic urethra (PSU).
  • To elucidate the role of the LMC in the emission phase of ejaculation.

Main Methods:

  • Histological analysis of 9 prostate and urinary bladder specimens using H&E, Masson's trichrome, and Verhoeff-van Gieson stains.
  • 3D reconstruction of 2 specimens using microcomputed tomography (micro-CT).

Main Results:

  • The LMC is composed of longitudinal muscle fibers located posterior to the ejaculatory ducts and prostatic utricle at the seminal colliculus.
  • The LMC extends from the seminal colliculus to the membranous urethra.
  • A mathematical model simulated LMC contractions.

Conclusions:

  • Histological and micro-CT analyses confirm the LMC extends from the seminal colliculus to the membranous urethra.
  • The LMC plays a critical role in ejaculation by facilitating seminal fluid ejection through coordinated contractions.