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Updated: Dec 28, 2025

Author Spotlight: Advancements in Refractive Surgical Correction for Presbyopia and Exploring Postoperative Visual Acuity
Published on: September 20, 2024
Refractive lens exchange with a trifocal intraocular lens in Fuchs endothelial dystrophy
Mayank A Nanavaty1, Zahra Ashena
1From the Sussex Eye Hospital, Brighton & Sussex University Hospitals NHS Trust (Nanavaty, Ashena), and Brighton & Sussex Medical School, University of Sussex (Nanavaty), Falmer, Brighton, United Kingdom.
Abstract:
A 57-year-old man with myopia presented with advanced Fuchs endothelial dystrophy, a refraction of -6.00 diopters (D) and -6.25 D, an endothelial cell count of 1100 cells/mm and 1000 cells/mm in right and left eyes, respectively, and corrected distance visual acuity of 20/30 in each eye. The patient was deemed unsuitable for excimer or femtosecond laser-based refractive surgery or refractive lens exchange (RLE) with a trifocal intraocular lens (IOL) alone because of the advanced Fuchs endothelial dystrophy and high risk of corneal decompensation and reduced optical quality postoperatively. A successful RLE with a hydrophobic trifocal IOL and Descemet membrane endothelial keratoplasty in both eyes was performed at an interval of 2 months between the eyes. At 12 months, the uncorrected distance visual acuity was 20/16 in each eye, with uncorrected near visual acuity of 20/20 for 40 to 60 cm from the face. The endothelial cell count at 12 months was 2250 cells/mm and 2120 cells/mm in right and left eyes, respectively.
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