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Diffusion Tensor Magnetic Resonance Imaging in Chronic Spinal Cord Compression
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Evaluating Spinal Canal Lesions Using Apparent Diffusion Coefficient Maps with Diffusion-Weighted Imaging.

Hirohito Kanamoto1, Masaki Norimoto1, Yawara Eguchi2

  • 1Department of Orthopaedic Surgery, Graduate School of Medicine, Chiba University, Chiba, Japan.

Asian Spine Journal
|February 14, 2020
PubMed
Summary
This summary is machine-generated.

Apparent diffusion coefficient (ADC) maps can objectively assess spinal canal lesions. This diffusion-weighted imaging technique aids in selecting patients for lumbar spinal stenosis (LSS) decompression surgery.

Keywords:
Apparent diffusion coefficient mapDecompression surgeryDiffusion-weighted imagingSpinal canal lesions

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Area of Science:

  • Radiology
  • Medical Imaging
  • Spinal Surgery

Background:

  • Lumbar spinal stenosis (LSS) surgery selection relies on subjective assessment and MRI, lacking objective standards.
  • Objective quantification is needed for improved surgical decision-making in LSS.

Purpose of the Study:

  • To evaluate apparent diffusion coefficient (ADC) maps in healthy volunteers and patients with spinal canal lesions.
  • To determine the utility of diffusion-weighted imaging (DWI) in assessing LSS.

Main Methods:

  • Performed 3T MRI on 10 healthy volunteers and 13 LSS patients.
  • Evaluated ADC values in the spinal canal at L4/5 and L5/S1 vertebrae.
  • Compared reduced and conventional field of view ADC measurements.

Main Results:

  • Significantly lower ADC values were observed at L4/5 in LSS patients compared to controls and L5/S1 in LSS patients.
  • An ADC cutoff value of 2.46 demonstrated high diagnostic performance (AUC 0.81, sensitivity 0.92, specificity 0.76) for LSS.
  • ADC mapping effectively visualized and quantified spinal canal lesions.

Conclusions:

  • Preoperative ADC map examination provides objective visualization and quantification of spinal canal lesions.
  • ADC mapping is a valuable tool for selecting patients for LSS decompression surgery.
  • This technique enhances objective decision-making in spinal stenosis treatment.