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Electrocardiographic Changes in Liver Cirrhosis-Clues for Cirrhotic Cardiomyopathy

Letitia Toma1,2, Adriana Mercan Stanciu1, Anca Zgura3

  • 1Department of Internal Medicine II, Fundeni Clinical Institute, 022328 Bucharest, Romania.

Medicina (Kaunas, Lithuania)
|February 14, 2020
PubMed

Insights

Electrocardiography (ECG) reveals significant cardiac changes in liver cirrhosis patients, indicating cirrhotic cardiomyopathy. These noninvasive ECG markers, including prolonged QT intervals, are crucial for diagnosing this condition.

Area of Science:

  • Cardiology
  • Hepatology
  • Medical Diagnostics

Background:

  • Cirrhotic cardiomyopathy is cardiac dysfunction in liver cirrhosis patients.
  • Electrocardiography (ECG) can detect cardiac changes related to liver disease.

Purpose of the Study:

  • Evaluate ECG changes in liver cirrhosis patients.
  • Compare ECG findings between cirrhosis and chronic hepatitis patients.

Main Methods:

  • Analyzed laboratory data and ECGs from 63 cirrhosis and 54 chronic hepatitis patients.
  • Assessed prolonged QT interval, QRS hypovoltage, and T-peak-to-T-end decrease.
  • Used echocardiography to confirm cirrhotic cardiomyopathy.

Main Results:

  • Advanced liver disease correlated with prolonged QT intervals.
  • Lower QRS amplitude observed in decompensated vs. compensated cirrhosis.
  • Accentuated T wave deceleration noted in cirrhosis patients.
  • ECG findings correlated with albumin, cholesterol, and ammonia levels.

Conclusions:

  • ECG changes are common in liver cirrhosis.
  • ECG alterations serve as important noninvasive markers for cirrhotic cardiomyopathy.

Keywords:
cirrhosis, electrocardiography, ammonia, serum bilirubin, hypoalbuminemia

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