Related Experiment Videos
Intravoxel incoherent motion imaging using steady-state free precession
1Diagnostic Radiology Department, Clinical Center, National Institutes of Health, Bethesda, Maryland 20892.
Magnetic Resonance in Medicine
|July 1, 1988
Summary
A new steady-state free precession (SSFP) method significantly speeds up intravoxel incoherent motion (IVIM) imaging. This faster SSFP technique shows greater sensitivity for IVIM compared to traditional spin-echo methods.
Area of Science:
- Magnetic Resonance Imaging
- Biomedical Engineering
- Medical Physics
Background:
- Intravoxel incoherent motion (IVIM) MR imaging provides in vivo diffusion and perfusion data.
- Conventional IVIM imaging utilizes spin-echo sequences, leading to lengthy acquisition times (over 17 minutes).
Purpose of the Study:
- To introduce a novel, rapid method for acquiring IVIM MR images.
- To evaluate the performance of the new method compared to existing techniques.
Main Methods:
- Development and application of a steady-state free precession (SSFP) sequence for IVIM acquisition.
- Comparison of SSFP-based IVIM with spin-echo based IVIM using phantom studies.
- Validation with in vivo imaging.
Main Results:
- The proposed SSFP method enables IVIM image acquisition in significantly reduced time (a few minutes).
- Phantom studies demonstrated superior sensitivity of SSFP to IVIM parameters compared to spin-echo sequences.
- Successful in vivo imaging was achieved using the SSFP-based approach.
Conclusions:
- SSFP is a promising technique for accelerating IVIM MR imaging.
- The enhanced sensitivity and speed of SSFP offer potential advantages for clinical applications of IVIM.