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Updated: Jun 22, 2026

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In Vitro Model of Physiological and Pathological Blood Flow with Application to Investigations of Vascular Cell Remodeling
Published on: November 3, 2015
Contributions of Ibn Alnafis to the correct understanding of the circulation
1Department of Pediatrics, The Ohio State University and Nationwide Children's Hospital, Columbus, OH, USA. ahmed.osman@nationwidechildrens.org.
Abstract
No abstract available in PubMed .
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The human circulatory system consists of blood, blood vessels that carry blood away from the heart, around the body, and back to the heart, and the heart itself, which acts as a central pump. The systemic circuit supplies blood to the whole body, the coronary circuit supplies blood to the heart, and the pulmonary circuit supplies blood flow between the heart and lungs.
Overview of the Cardiovascular System
The cardiovascular system is a vital transportation system in the body. It comprises the heart and blood vessels and facilitates the exchange of gases, nutrients, and waste products.
Heart
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Blood Vessels
Blood...
Heart
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Blood Vessels
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Overview of Systemic and Pulmonary Circulation
The systemic and pulmonary circuits are crucial components of the circulatory system, working together to transport blood between the heart, lungs, and the rest of the body. The process begins with pulmonary circulation, where deoxygenated blood is pumped from the right ventricle to the lungs via the pulmonary trunk and arteries. Upon reaching the lungs, the blood becomes oxygenated and returns to the heart, specifically to the left atrium, via the pulmonary veins.
The oxygenated blood is sent...
The oxygenated blood is sent...
Overview of Systemic Arteries
The human body is a complex, well-organized machine, and at the heart of its operations lies the circulatory system. This network of blood vessels, which includes systemic arteries, plays a vital role in maintaining life by transporting nutrients, oxygen, and waste products to and from cells throughout the body.
Systemic circulation is the part of the cardiovascular system that carries oxygenated blood away from the heart to the body's tissues and returns deoxygenated blood back to the heart.
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Blood flow through a cylindrical blood vessel can be mathematically described using the principles of laminar flow, a regime in which fluid moves smoothly in parallel layers. In this model, the velocity of the blood is not uniform across the cross-section of the vessel; rather, it varies with the radial distance from the center. The maximum velocity occurs along the central axis, decreasing progressively toward the vessel walls, where it reaches zero due to viscous drag.Approximating Blood...
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Stokes’ Theorem provides a fundamental connection between the circulation of a vector field along a closed boundary and the cumulative rotational behavior across the surface it encloses. For a smooth three-dimensional surface with an oriented boundary curve, this theorem offers a unified way to relate motion along the edge to local rotational effects distributed over the surface.Mathematical FormulationThe theorem states that the circulation of a vector field along a closed curve is equal to...

