Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Gastrointestinal contrast agents: a diamagnetic approach.

J J Listinsky1, R G Bryant

  • 1Department of Radiology, University of Rochester Medical Center, New York 14642.

Magnetic Resonance in Medicine
|November 1, 1988
PubMed
Summary

Kaolin and bentonite clay minerals show promise as gastrointestinal contrast agents for MRI. These non-toxic agents effectively eliminate signals across all clinical field strengths, ensuring reliable imaging.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Chromium(III) complexes as intermolecular probes.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2005
Same author

Anomalous surface diffusion of water compared to aprotic liquids in nanopores.

Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics·2002
Same author

Cell surface fucose ablation as a therapeutic strategy for malignant neoplasms.

Advances in anatomic pathology·2001
Same author

Surface nuclear magnetic relaxation and dynamics of water and oil in macroporous media.

Physical review. E, Statistical, nonlinear, and soft matter physics·2001
Same author

New ways of probing surface nuclear relaxation and microdynamics of water and oil in porous media.

Magnetic resonance imaging·2001
Same author

Molecular oxygen spin-lattice relaxation in solutions measured by proton magnetic relaxation dispersion.

Journal of magnetic resonance (San Diego, Calif. : 1997)·2001

Area of Science:

  • Materials Science
  • Biomedical Imaging
  • Radiology

Background:

  • Magnetic Resonance Imaging (MRI) requires effective contrast agents for visualizing gastrointestinal structures.
  • Current contrast agents may have limitations in terms of safety, efficacy, or field strength dependence.
  • Clay minerals offer potential as novel contrast agents due to their unique properties.

Purpose of the Study:

  • To evaluate kaolin and bentonite clay minerals as gastrointestinal (GI) contrast agents for MRI.
  • To assess the effectiveness and safety of these clay-based agents.
  • To determine their performance across various MRI field strengths.

Main Methods:

  • Characterization of kaolin and bentonite clay minerals.
  • In vitro and/or in vivo testing of clay minerals as GI contrast agents in MRI.

Related Experiment Videos

  • Evaluation of signal elimination and relaxation efficiency at different magnetic field strengths.

    • Main Results:

    • Kaolin and bentonite demonstrated efficacy as GI contrast agents for MRI.
    • The relaxation efficiency of these agents exhibited weak field dependence.
    • The agents were found to be non-toxic and effectively eliminated signals in their vicinity.

    Conclusions:

    • Kaolin and bentonite are viable, non-toxic gastrointestinal MRI contrast agents.
    • Their effectiveness is consistent across all clinically relevant MRI field strengths.
    • These clay minerals represent a promising alternative for GI imaging applications.