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Four ways of becoming ill
1USDA, Human Nutrition Research Center, Grand Forks, ND 58202.
Medical Hypotheses
|September 1, 1988
Summary
Human illnesses stem from four main causes: toxicity, heredity, infection, and deficiency. Complex diseases arise from interactions between these factors, explaining health variations.
Area of Science:
- Medical Science
- Pathology
- Etiology
Background:
- Diseases are categorized based on the comprehensibility of their causes.
- Comprehensible etiologies are grouped into four primary classes: toxicity, heredity, infection, and deficiency.
Purpose of the Study:
- To classify illnesses based on their etiologic agents.
- To explore the concept of cooperating etiologic agents in disease development.
- To explain disease variability through the interaction of these agents.
Main Methods:
- Classification of diseases by comprehensible and incomprehensible etiologies.
- Categorization of comprehensible diseases into four classes: toxicity, heredity, infection, and deficiency.
- Illustration of disease concepts through the cooperation of two, three, or four etiologic classes.
Main Results:
- Identified four fundamental classes of etiologic agents for comprehensible diseases.
- Demonstrated how interactions (cooperations) between these agents lead to various illnesses like hereditary intoxication and infectious deficiency.
- Provided examples of diseases requiring the cooperation of three or four etiologic classes.
Conclusions:
- There are only four known fundamental ways for humans to develop illnesses.
- The interaction and cooperation among these four basic etiologic agents can account for significant variability observed in human diseases.