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Related Concept Videos

Burn Injuries01:22

Burn Injuries

3.9K
Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...
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Decreased Body Temperature01:29

Decreased Body Temperature

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A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by...
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Inflammatory Response01:28

Inflammatory Response

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An inflammatory response is a localized, nonspecific immune reaction that occurs when a tissue is injured. It is characterized by redness, swelling, heat, and pain, which are commonly called the cardinal signs and symptoms of inflammation. Inflammation can sometimes result in a loss of function.
Inflammation can be triggered by various stimuli, such as impact, abrasion, chemical irritation, infections, and extreme hot or cold temperatures. These can damage cells and connective tissue fibers,...
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Flail Chest-II01:26

Flail Chest-II

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Managing flail chest, a condition characterized by a segment of the chest wall moving independently from the rest of the thoracic cage, requires a comprehensive approach. It includes a thorough assessment of the patient's condition, a diagnostic evaluation to determine the extent of the injury, and the implementation of appropriate medical interventions tailored to the individual's needs.
Assessment:
1. Clinical Evaluation:
History:
453

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Related Experiment Video

Updated: Dec 28, 2025

Severe Burn Injury in a Swine Model for Clinical Dressing Assessment
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Burn injury.

Marc G Jeschke1,2, Margriet E van Baar3,4, Mashkoor A Choudhry5

  • 1Ross Tilley Burn Center, Department of Surgery, Sunnybrook Health Science Center, Toronto, Ontario, Canada. marc.jeschke@sunnybrook.ca.

Nature Reviews. Disease Primers
|February 15, 2020
PubMed
Summary

Burn injuries cause significant physical and mental health issues, impacting long-term quality of life. Effective burn care requires addressing acute, critical, and rehabilitation challenges, alongside societal stigmata.

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Area of Science:

  • Trauma and Burn Surgery
  • Critical Care Medicine
  • Rehabilitation Medicine

Background:

  • Burn injuries are severe medical events with high rates of morbidity and mortality.
  • Severe burns trigger complex immune, inflammatory, and metabolic responses, potentially leading to organ failure.
  • The impact of burns extends beyond physical healing, affecting patients' mental health and overall quality of life.

Purpose of the Study:

  • To provide a comprehensive overview and update on current burn care practices.
  • To highlight the multifaceted challenges in managing burn injuries, from acute care to long-term rehabilitation.
  • To raise awareness regarding the persistent challenges and social stigmata associated with burn injuries.

Main Methods:

  • This primer synthesizes current knowledge on burn injury management.
  • It reviews the pathophysiology, clinical manifestations, and treatment modalities for burn patients.
  • The content addresses both immediate critical care and long-term recovery aspects.

Main Results:

  • Burn injuries necessitate integrated management strategies addressing physical, psychological, and social recovery.
  • Successful burn care extends beyond wound healing to encompass comprehensive rehabilitation and support.
  • Multidisciplinary approaches are crucial for optimizing patient outcomes and quality of life.

Conclusions:

  • Burn care requires a holistic approach, recognizing the profound and lasting effects of injury.
  • Addressing the physical, mental, and social sequelae of burns is essential for patient recovery.
  • Increased awareness and improved management strategies are needed to mitigate the long-term burden of burn injuries.