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Updated: Dec 28, 2025

A Label-free Technique for the Spatio-temporal Imaging of Single Cell Secretions
Published on: November 23, 2015
Chemical communication in spatially organized protocell colonies and protocell/living cell micro-arrays
Xuejing Wang1,2, Liangfei Tian2, Hang Du1
1State Key Laboratory of Urban Water Resource and Environment , School of Chemistry and Chemical Engineering , Harbin Institute of Technology , Harbin , 150001 , China .
Abstract:
Micro-arrays of discrete or hemifused giant unilamellar lipid vesicles (GUVs) with controllable spatial geometries, lattice dimensions, trapped occupancies and compositions are prepared by acoustic standing wave patterning, and employed as platforms to implement chemical signaling in GUV colonies and protocell/living cell consortia. The methodology offers an alternative approach to GUV micro-array fabrication and provides new opportunities in protocell research and bottom-up synthetic biology.
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