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Related Concept Videos

The Thyroid Gland01:23

The Thyroid Gland

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The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Synthesis and Regulation of Thyroid Hormones01:20

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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Related Experiment Video

Updated: Dec 28, 2025

In Vivo Inhibition of MicroRNA to Decrease Tumor Growth in Mice
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Thyroid follicular microcarcinoma.

Andrea Casaril1, Marco Inama1, Harmony Impellizzeri1

  • 1Endocrine Surgery Unit, Pederzoli Hospital, Peschiera del Garda, Verona, Italy.

Gland Surgery
|February 15, 2020
PubMed
Summary
This summary is machine-generated.

Follicular thyroid microcarcinoma (mFTC) lacks management guidelines due to limited data. This review synthesizes current literature to provide suggestions for mFTC treatment, addressing a critical gap in thyroid cancer care.

Keywords:
Follicular carcinomafollicular microcarcinomafollicular tumorthyroid cancerthyroid neoplasm

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Area of Science:

  • Endocrinology
  • Oncology
  • Pathology

Background:

  • Differentiated thyroid cancers are common, with papillary types having a favorable prognosis.
  • Follicular thyroid cancer is more aggressive, prone to distant metastases.
  • Papillary microcarcinoma management has evolved towards less invasive approaches.

Purpose of the Study:

  • To review current literature on follicular thyroid microcarcinoma (mFTC).
  • To provide management suggestions for mFTC in the absence of robust evidence.
  • To address the low incidence and limited research on mFTC.

Main Methods:

  • Literature review of existing studies on mFTC.
  • Synthesis of available data on mFTC incidence and behavior.
  • Analysis of management strategies for similar thyroid microcarcinomas.

Main Results:

  • Limited data and studies exist for mFTC.
  • mFTC incidence is low, contributing to research scarcity.
  • Current literature does not provide effective management guidelines for mFTC.

Conclusions:

  • There is a significant lack of evidence-based guidelines for managing mFTC.
  • Further research is crucial to establish optimal treatment protocols for mFTC.
  • This review aims to offer preliminary management insights for mFTC.