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Related Concept Videos

Urine Studies II: Urine Culture and Sensitivity Test01:26

Urine Studies II: Urine Culture and Sensitivity Test

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A urine culture and sensitivity test is a diagnostic procedure used to identify urinary tract bacterial infections and determine the most effective antibiotics for treatment. This test is generally preferred when a patient shows manifestations of a urinary tract infection, such as frequent or painful urination, cloudy or foul-smelling urine, or lower abdominal pain.Purpose of the TestThe primary goals of a urine culture and sensitivity test are to:Determine the specific bacteria causing the...
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Acute Pyelonephritis II: Diagnostic Studies and Management01:28

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Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
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Sputum Studies II: Culture and Sensitivity01:20

Sputum Studies II: Culture and Sensitivity

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Description
Sputum culture and sensitivity is a medical procedure used to diagnose bacterial infections in the respiratory tract and select the most appropriate antibiotics for treatment. This process involves analyzing sputum samples of thick and opaque secretions produced in the lungs and airways. These samples are collected from patients and then sent to the laboratory for analysis.
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Acute Kidney Injury IV: Diagnostic Studies and Prevention01:30

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Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
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Blood Studies I: ABG and VBG01:26

Blood Studies I: ABG and VBG

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Blood studies are critical in the medical field, enabling healthcare professionals to assess a patient's health status accurately. This page will focus on two significant blood studies: Arterial Blood Gas (ABG) and Venous Blood Gas (VBG).
Arterial Blood Gas (ABG)
Arterial Blood Gas (ABG) studies are crucial for assessing the lungs' ability to supply oxygen and remove carbon dioxide, reflecting the patient's ventilation status. They also help understand the kidneys' capacity to...
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Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care01:30

Urinary Tract Infection III: Diagnostic Studies and Interprofessional Care

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A healthcare provider can diagnose a urinary tract infection (UTI) through several methods:Medical History and Symptoms: The provider will take a detailed medical history and ask about symptoms such as frequent urination, burning sensation during urination, and lower abdominal pain.Urinalysis: A clean-catch urine sample is collected in a sterile container and tested for the presence of bacteria, white blood cells (leukocytes), nitrites, blood, and protein. The presence of leukocytes and...
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Preparation of a Blood Culture Pellet for Rapid Bacterial Identification and Antibiotic Susceptibility Testing
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Two Blood Cultures With Age-Appropriate Volume Enhance Suspected Sepsis Decision-Making.

Paul Tran1, Elaine Dowell2, Stacey Hamilton2

  • 1Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA.

Open Forum Infectious Diseases
|February 15, 2020
PubMed
Summary
This summary is machine-generated.

Implementing electronic medical record (EMR) decision support for multiple blood cultures in children significantly improved pathogen detection and antimicrobial stewardship. This approach enhances diagnostic accuracy for serious bacterial infections (SBI) in pediatric patients.

Keywords:
antibioticsbacteremiablood culturesepsis

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Area of Science:

  • Pediatric Infectious Diseases
  • Clinical Microbiology
  • Health Informatics

Background:

  • Multiple blood cultures enhance pathogen detection and antimicrobial stewardship in adults with serious bacterial infections (SBI).
  • Pediatric practices often use single, low-volume blood cultures, complicating diagnosis and treatment.
  • Standardizing blood culture protocols in children is crucial for accurate diagnosis.

Purpose of the Study:

  • To evaluate the impact of electronic medical record (EMR) decision support on blood culture practices in children.
  • To assess changes in pathogen yield, isolate classification, and antimicrobial modifications post-intervention.
  • To determine the effectiveness of age-based volume recommendations for pediatric blood cultures.

Main Methods:

  • Implementation of EMR decision support recommending 2 blood cultures before antibiotics for suspected SBI in children.
  • Age-based volume calculation for blood cultures, differing from weight-based methods.
  • Comparative analysis of inpatient children's blood culture data from pre-intervention (2008-2009) and post-intervention (2011-2013) periods.

Main Results:

  • Significant increase in multiple blood cultures collected before antibiotics (88.0% vs 12.3%).
  • Higher percentage of cultures with recommended volumes (74.3% vs 15.2%).
  • Improved pathogen isolation rates and more appropriate antimicrobial treatment decisions were observed.

Conclusions:

  • Multiple blood cultures with age-based volumes, collected before antibiotic administration, enhance pathogen isolation in children.
  • This strategy improves antimicrobial treatment modifications and diagnostic accuracy for pediatric serious bacterial infections.
  • EMR decision support effectively promotes optimal blood culture practices in pediatric care.