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Orthotopic Xenograft Mouse Model in Esophageal Squamous Cell Carcinoma
Valen Z Yu1, Joseph C Y Ip2,3, Josephine M Y Ko2,3
1Department of Clinical Oncology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong. zvyu@hku.hk.
Methods in Molecular Biology (Clifton, N.J.)
|February 15, 2020
Abstract:
Orthotopic xenograft model recapitulates the faithful organ-specific microenvironment and facilitates analyses involving tumor-stromal interactions that are crucial for developing new-generation cancer therapy. Herein, we describe the detailed rationales and protocols of a versatile orthotopic xenograft model for esophageal squamous cell carcinoma.

