Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Sample Preparation for Analysis: Overview

Sample Preparation for Analysis: Overview

Sample preparation is an essential step in the analytical process. It involves preparing a sample so that it can be analyzed accurately. The goal is to extract the analyte, the substance you want to measure, from the sample while removing any components that may interfere with the analysis. Sample preparation techniques vary depending on the physical state of the sample.
Bulk or large solid samples are typically reduced in size using grinding, crushing, or milling techniques to increase the...

Sample Preparation for Analysis: Advanced Techniques

Sample Preparation for Analysis: Advanced Techniques

Accurate analysis of complex samples often requires advanced preparation techniques to achieve reliable and reproducible results. Samples containing inorganic or organic materials can be challenging to dissolve or decompose effectively. Standard sample preparation methods include acid digestion, fusion, dry ashing, and wet digestion.
Acid digestion with strong acids is commonly used to dissolve inorganic materials that are insoluble (do not dissolve) in water. This method can be useful for...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

On-chip integration of electromembrane extraction and thin-film solid-phase microextraction using polyaniline/graphene oxide composite for determination of synthetic dyes in beverage and environmental samples.

Analytical methods : advancing methods and applications·2025

Same author

Hydrophobic Deep Eutectic Solvents as New Supported Liquid Membranes for Extraction of β-Blockers by Hollow Fiber-Electromembrane Extraction.

Journal of separation science·2025

Same author

In-tube solid-phase microextraction of polycyclic aromatic hydrocarbons from refinery water samples using UiO-66/polyacrylonitrile electrospun nanofibers followed by high-performance liquid chromatography-ultraviolet detection.

Journal of separation science·2024

Same author

Nanoplastic Sample Cleanup by Micro-Electromembrane Extraction across Free Liquid Membranes.

Analytical chemistry·2024

Same author

Three-Dimensional Network of Highly Uniform Cobalt Oxide Microspheres/MXene Composite as a High-Performance Electrocatalyst in Hydrogen Evolution Reaction.

ACS applied materials & interfaces·2024

Same author

Bidimensional Dynamic Magnetic Levitation: Sequential Separation of Microplastics by Density and Size.

Analytical chemistry·2024

Same journal

Chromatographic Purification of Complex Natural Products as a Decision Problem: Retention Prediction, Adaptive Optimization, and Experimental Feedback.

Journal of separation science·2026

Same journal

A High-Throughput Analytical Approach Using Polyaniline Doped With Oxalic Acid in Thin Film Solid-Phase Microextraction for the Determination of Personal Care Products in Recreational Waters.

Journal of separation science·2026

Same journal

Simultaneous Determination of Dechlorane-Related Compounds in Fish Muscle by Microwave-Assisted Extraction Combined With Enhanced Matrix Removal for Lipids Cleanup and Gas Chromatography-Tandem Mass Spectrometry.

Journal of separation science·2026

Same journal

Covalent Zwitterionic Peptide-Based Antifouling Coating of the Fused Silica Capillary Applied for CE Separation of Proteins.

Journal of separation science·2026

Same journal

Pharmacokinetic Study of Five Lead Components of Psoraleae Fructus in Human Serum by UHPLC-Q-TOF-MS and UHPLC-QqQ-MS/MS after Oral Administration of Qing'e Pills.

Journal of separation science·2026

Same journal

Passive Blood-Plasma Separation via Constriction-Expansion Geometry in Untreated Paper Microfluidic Devices.

Journal of separation science·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Dec 28, 2025

Stereolithographic 3D Printing with Renewable Acrylates

Stereolithographic 3D Printing with Renewable Acrylates

Published on: September 12, 2018

3D Printing in analytical sample preparation.

Feng Li¹, Melisa Rodas Ceballos¹, Sepideh Keshan Balavandy¹

¹Australian Centre for Research on Separation Science (ACROSS), School of Natural Sciences. Chemistry, University of Tasmania, Hobart, Tasmania, Australia.

Journal of Separation Science

|February 15, 2020

Summary

This summary is machine-generated.

Additive manufacturing, or 3D printing, rapidly creates cost-effective analytical sample preparation devices. This technology advances automated methods and enables new extraction techniques for improved analysis.

Keywords:

3D printing liquid-liquid extraction membrane separation sample preparation solid-phase extraction

More Related Videos

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization

Published on: February 18, 2022

3D Printing of Preclinical X-ray Computed Tomographic Data Sets

3D Printing of Preclinical X-ray Computed Tomographic Data Sets

Published on: March 22, 2013

Related Experiment Videos

Last Updated: Dec 28, 2025

Stereolithographic 3D Printing with Renewable Acrylates

Stereolithographic 3D Printing with Renewable Acrylates

Published on: September 12, 2018

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization

3D Printing and In Situ Surface Modification via Type I Photoinitiated Reversible Addition-Fragmentation Chain Transfer Polymerization

Published on: February 18, 2022

3D Printing of Preclinical X-ray Computed Tomographic Data Sets

3D Printing of Preclinical X-ray Computed Tomographic Data Sets

Published on: March 22, 2013

Area of Science:

Analytical Chemistry
Materials Science
Chemical Engineering

Background:

Additive manufacturing (3D printing) has become crucial in analytical sample preparation over the last five years.
It facilitates cost-effective and rapid fabrication of devices, particularly for flow-based analysis and automated methods.

Purpose of the Study:

To review the current state-of-the-art of 3D printing applications in analytical sample preparation.
To highlight recent advances and emerging possibilities in device fabrication and material utilization.

Main Methods:

Fabrication of membrane-based separation devices using print-pause-print and multi-material 3D printing.
Development of 3D printed holders for solid-phase extraction with various sorbent materials (beads, disks, fibers, magnetic particles).
Direct 3D printing of extraction sorbents, functionalization of printable resins, and coating of devices with nanomaterials.

Main Results:

3D printing enables the creation of novel and improved devices for solid-phase extraction and liquid-liquid extraction.
Advances include integrated separation devices, functionalized materials, and enhanced extraction chambers.
The technology supports the development of automated analytical workflows and high-performance liquid chromatography (HPLC) coupled methods.

Conclusions:

3D printing is a transformative technology for analytical sample preparation, offering versatile and accessible fabrication solutions.
It significantly expands the possibilities for developing innovative, automated, and efficient analytical methods.
Continued advancements in materials and printing techniques promise further integration and performance improvements.